Improved sequence variant analysis strategy by automated false positive removal
نویسندگان
چکیده
منابع مشابه
Improved sequence variant analysis strategy by automated false positive removal
Sequence variant analysis (SVA) is critical in therapeutic protein development because it ensures the absence of genetic mutations of a production clone or high-level misincorporations during cell culture. While software for searching sequence variants from mass spectrometry data are available, effectively distinguishing true positives from a large number of false positives in the reported hits...
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ژورنال
عنوان ژورنال: mAbs
سال: 2017
ISSN: 1942-0862,1942-0870
DOI: 10.1080/19420862.2017.1336591